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Magnolia bark contains two anti-inflammatory substances, magnolol and honokiol, which reportedly inhibit the activation of NF-KB, a key mediator in both inflammatory and aging processes. However, with age, the immune system becomes less effective and inflammatory activity increases. This can lead to chronic inflammation characterized by a slow but continuous production of free radicals that in turn, cause wrinkles and sagging skin.
Although magnolol and honokiol exhibit low solubility in water, the company has developed a technique to make a magnolia preparation that is both water-dispersible and rich in these active compounds. In vivo studies have shown that the compund also reduces facial skin redness and improves the hydration and visco-elastic properties of the skin, notably on the crow’s feet area.
The compound is recommended at 0.1–0.5 % in: antiaging products for face and eye contour, protective formulas and anti-redness skin care. The compound can be dissoved in the aqueous phase or pre-dispersed in up to 20% in water and added to formulations during the cooling phase (< 60°C). Temperatures of up to 80°C for a short time do not affect the stability of the compound.